With that, here's how to get every character in The Binding of Isaac - from the originals to the newer Repentance additions. RELATED: The Binding Of Isaac: How To Become Guppy While Isaac is great, doubly so when you get the D6, every character has their own unlocks tied to their progression which benefits you regardless of who you select on the next run, so they're worth taking for a spin. Throw in the DLCs and you have a game jampacked with others besides the titular character. They can even be upgraded, so there's a lot to unpack when it comes to Isaac's character selection screen, and not all of the unlocks are immediately visible. Samson deals more damage the more he takes, Azazel starts with a shorter-range Brimstone, and Eden is randomized each run. To unlock the new character Jaboc and Esau is actually a massive challenging task as it comes in many different parts. The Binding of Isaachas a lot of characters, each with their own perks. The next downloadable content for The Binding of Isaac: Rebirth is now available, called Repentance, and with it comes a plethora of changes and updates, as well as some new characters Heres how to get Jacob and Esau How to Unlock Jacob in Binding of Isaac Repentance.